The upper sections of the Ontonagon River are renowned for their abundant trout populations, particularly brook and brown trout. This stretch features calm pools interspersed with rocky riffles, creating an ideal habitat for fly fishing. Anglers will appreciate the easy access from forest roads near M-28 and the serene atmosphere of this more remote area.

The mouth of the river, where it meets Lake Superior at Ontonagon Harbor, offers exceptional fishing, particularly during the spring and fall runs. King salmon and steelhead move upstream during these times, drawing anglers looking to hook trophy-sized fish. The harbor also provides amenities like parking, boat ramps, and shoreline spots for casting.

The East Branch of the Ontonagon River is a prime location for smallmouth bass fishing. With its deeper holes and undercut banks, this stretch of the river is ideal for spin casting or live bait fishing. Just a short drive from Bruce Crossing, it’s easily accessible for a day trip.

The Ontonagon River has a rich historical connection to the area's lumber and mining industries, which shaped its surrounding communities. Many of the river's access points were once logging sites, now reclaimed by nature and transformed into peaceful, rustic fishing spots.

Spring (April-May) and fall (September-November) for salmon, summer for trout and bass.

Fly rods, spinning rods, polarized sunglasses, bug spray, and a Michigan fishing license.

From the Porcupine Mountains area, take M-64 or M-28 to reach various access points along the river; travel times range from 15-45 minutes depending on the location.